Regardless of your Anadrol doses, where they may fall, no man should use this steroid for more than eight weeks. In fact, most men should not extend use past six weeks if they are going to protect their health. Use that extends past six weeks also appears to provide little benefit in terms of growth, meaning there’s really no point in extending use. Many men will find the bulk of the results occur within the first four weeks of use regardless of the Anadrol doses. This makes 4-6 weeks the perfect time frame for most men. Such a time frame of use will be the safest and will typically produce all the desired and obtainable results of this steroid.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are