Ovidrel is a fertility drug that is designed to initiate ovulation in women who are having trouble conceiving. It is typically given as an at-home injection subcutaneously (under the skin) in a different site each time. For example, you might inject Ovidrel near the belly button one time, then in the back fat of the upper arm the next time, and the fatty outer thigh area the time after that. Clean the injection site thoroughly, wash your hands, and prepare the syringe. Injection is easy, but make sure to follow your doctor’s instructions and monitor your symptoms closely.